Contraindications for Dapoxetine

Who Can Use Priligy?

Known as a magic pill, Priligy is recommended to be used by men suffering from premature ejaculation (PE). The term “premature” has been defined by the medical and pharmacological industry as an ejaculation that occurs uncontrollably soon.

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The problem of PE often accompanies other sexual disorders, such as erectile dysfunction. In these instances, combination therapy with PDE5 inhibitors is indicated.

Priligy should only be used by patients experiencing PE when prescribed by a healthcare provider. However, this medication should not be used if you demonstrate a contraindication for any of the active or non-active ingredients of Priligy, such as peanut or soy products, which can amplify the sensitivity of this medication.

Since Priligy is classified as an antidepressant drug interacting with serotonin in the brain, the use of this medication is not recommended for individuals with a history of drug and alcohol abuse.

Dapoxetine and Other Medicines

Dapoxetine is contraindicated when used in combination with monoamine oxidase inhibitors (MAOIs). In exceptional cases, linezolid (i.e., antibiotic that is a non-selective MAO inhibitor) can be administered in combination with Dapoxetine under medical supervision to monitor serotonin syndrome symptoms and control blood pressure.

Treatment using Dapoxetine may be initiated two weeks following the discontinuation of an irreversible MAOI, or >24 hours following treatment with a reversible MAO inhibitor demonstrating a short half-life (e.g., moclobemide, linezolid, methylthioninium chloride, and blue Methylene are non-selective reversible MAO inhibitors). In contrast, at least a one week period should be allowed for between discontinuation of Dapoxetine and the initiation of therapy with an MAOI.

Dapoxetine should also not be used in combination with thioridazine or other drugs that inhibit the CYP450 2D6 hepatic enzyme. Taking Dapoxetine may raise plasma thioridazine levels. Administration of thioridazine alone may lead to prolongation of the QTc interval associated with severe ventricular arrhythmias such as torsades de pointes and sudden cardiac death. Dapoxetine should also not be used in combination with the drug pimozide.

Priligy and Viagra

Since the intended use of Priligy is to treat PE, which is often associated with other sexual dysfunctions, asking the question of whether this medication is compatible with Viagra, Cialis, Levitra, and other drugs used to treat erectile dysfunction are relevant.

Research studies have shown that Priligy and Viagra, as well as other PDE5 inhibitors, can be taken safely when taken in prescribed dosages and provider instructions. When taken in combination with Viagra, Priligy can significantly improve the quality of sexual life and solve problems associated with erectile dysfunction and PE.